简兮从小失去父母，由祖母抚养长大，却依然成为一个乐观积极的少女。祖母去世后，简兮独自离开故乡，远赴北京寻找亲生母亲。遭到母亲展眉的冷漠拒绝后，简兮没有灰心丧气，反而立志成为一个出色的表演艺术家。凭着对表演的一腔热情和杰出天赋，简兮塑造出鲜明各异的角色，成为受到大众欢迎的女演员。唐斐的表演事业已攀巅峰，个性却霸道任性、自以为是；直到认识简兮后，他才开始重新审视自己的人生，早已遗忘的亲情与梦想也逐渐复苏，两人从斗气冤家发展成一对人人羡慕的爱侣。简兮和唐斐在对艺术的追寻过程中，不断追求自由与尊严，坚持自我实现，最终获得幸福，并以他们的勇气证实着生命的力量。
云巅之上第2季第25集
失去对手的季晴难掩内心的伤感并打电话让唐斐制止简兮。唐斐带简兮去医院探望左念，简兮看到可怜的左念转身离去，简兮说唐斐都不肯原谅自己的父亲让唐斐无力反驳。在候机室里，唐斐找到简兮告诉她自己原谅了自己父亲韩正德。在唐斐的劝解下，简兮偷偷捐赠了造血干细胞救了左念。唐斐去医院找简兮却被粉丝缠住，眼睁睁看着简…
云巅之上第2季第24集
第二天的记者采访中，展眉一改往日作风，在记者面前大赞简兮。陆周带简兮到医院看到了左念，简兮知道展眉的故意示好只是为了让她捐献造血干细胞，简兮恨透了展眉。简兮在接下来的拍摄中，她故意让展眉在片场难堪，简兮走过去质问展眉并告诉她自己不会救左念。齐文森故意在简兮参加的《真情告白》节目中让主持人说出简兮是展…
云巅之上第2季第23集
饰演简兮妈妈的女演员临时有事，展眉过来饰演她的妈妈，简兮得知后十分生气。简兮在一场跳舞戏后病情发作，站在一旁的展眉虽语言犀利内心却是满满的担心。安心看简兮忍痛练习去找陆周，陆周将她驳回。伤心的安心又遇岳乐调侃，岳乐见安心如此伤心上前安慰，最后两人相拥亲吻。第二天简兮跳舞这场戏十分的顺利，受到导演认可…
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