《王大花的革命生涯》是由简川訸执导的一部谍战悬疑剧，闫妮、张博、辛芷蕾、高峰等主演。
该剧讲述了一个来自于农村的具有喜剧人格的女性人物王大花，她用亲身经历写就了一部农村妇女在国难当头的大背景下走向革命并完成自身成长的故事 。
1937年，日军的铁骑在中华大地上肆虐。中共地下党员夏家河带着电台前往沦陷区大连，赴交通站接头时，
意外碰见当年的初恋女友王大花，王的丈夫唐全礼误以为两人旧情复燃，打乱了夏的计划，两人同时被捕入狱，入狱前夏将电台托付于王大花。王大花倾其家产欲救出两人，但丈夫却蒙冤而死，得救的只有夏家河。对夏抱有成见的王大花稀里糊涂将电台带至大连，引出重重危机，几经辗转终于成功交付共产党。王大花为谋生，在大连开起饭店，与夏家河所开的诊所共处一街，两人逐渐从冤家到相依相帮，历经磨难，屡次完成革命任务，立下奇功。在夏家河的引导下，王大花终于从一名普通的家庭妇女成长为一个坚定的共产主义战士 。
青木放出消息，只有大花才能挽救孩子的命。情报必须及时送出去，夏家河让大花去送情报，自己去救孩子，大花强烈反对。大花用口传的方式将情报内容一一说给了夏家河。大花出现，青木假意释放孩子，但几名日本特务随后追上孙云香和孩子欲下手。关键时刻，夏家河出现救了他们，并安排刘顺保护。夏家河出现在客栈，他亲手为大花…
麻姑说要去花园口见大花拿情报，江桂芬隐隐感觉不对。二人回到客栈，夏家河、大花见到麻姑惊讶。谈话间，麻姑自称是“大姑娘”，希望大花能够尽快将“天火计划”交给她。仨人意识到麻姑是日本特务，于是将计就计，做局演戏。麻姑和青木接头被刘顺发现，刘顺立刻通知夏家河。众人决定将假情报借麻姑之手传给青木，夏家河预测…
麻姑说要去花园口见大花拿情报，江桂芬隐隐感觉不对。二人回到客栈，夏家河、大花见到麻姑惊讶。谈话间，麻姑自称是“大姑娘”，希望大花能够尽快将“天火计划”交给她。仨人意识到麻姑是日本特务，于是将计就计，做局演戏。麻姑和青木接头被刘顺发现，刘顺立刻通知夏家河。众人决定将假情报借麻姑之手传给青木，夏家河预测…
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